Aastha Shori,Yashumati Ratan and Ashutosh Pareek Synthesis of Bioactive Natural Phenolics & their Anti oxidant Activity
In this context, the realm of “Green Chemistry” becomes highly relevant. Besides their pharmacological importance, phenolics are also widely employed as flavors, pigments, and nutritional components in the food industry. Out of all antioxidant activity is one of the most frequently explored. Similarly resveratrol, a trihydroxy-(E)-stilbene has been shown to act as an effective AhR antagonist and is in advanced stage of clinical trial for treatment of various cancer. The goal of green chemistry is to create better, safer chemicals while choosing the safest, most efficient ways to synthesize... Consequently, the development of environmentally friendly approaches towards bioactive molecules is the need of the hour. Phenolics have been found to possess potent biological activities including hypolipidemic, anticancer, anti-HIV, anti-malarial and anti-asthmatic activities. Similarly neolignans show antioxidant and cytotoxic activities (such as podophylotoxin shows anticancerous activity).